Primal Defense® is created using the following probiotic species or their enzymes:
- Lactobacillus acidophilus
- Lactobacillus rhamnosus
- Lactobacillus salivarius
- Lactobacillus plantarum
- Lactobacillus paracasei
- Lactobacillus casei
- Lactobacillus brevis
- Bifidobacterium bifidum
- Bifidobacterium breve
- Bifidobacterium lactis
- Bifidobacterium longum
- Bacillus subtilis
- Saccharomyces boulardii